alpha Fetoprotein anticorps (AA 19-210)
Aperçu rapide pour alpha Fetoprotein anticorps (AA 19-210) (ABIN7539788)
Antigène
Voir toutes alpha Fetoprotein (AFP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 19-210
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Fonction
- AFP Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human AFP (AA: 19-210) expressed in HEK293-6e cells supernatant.
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Isotype
- IgG2b
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Autre désignation
- AFP
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Sujet
- This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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Poids moléculaire
- 68.6 kDa
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ID gène
- 174
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UniProt
- P02771
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Pathways
- C21-Steroid Hormone Metabolic Process
Antigène
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